Endocrine Abstracts

Our objective was to estimate the distribution of Spanish diabetic patients attending to individualized glycaemic targets recommended by the ADA/EASD consensus with and without considering hypoglycaemia risk. We conducted a cross-sectional study in a Spanish primary care setting between 2011 and 2012. A total of 5382 type 2 diabetic subjects under antihyperglycaemic treatment for at least 3 months prior to inclusion completed a study visit in which clinical data including age,...

Persistent Mullerian duct syndrome (PMDS) is a rare disorder of sex development characterized by the persistence of Mullerian duct derivatives in a genotypic (46,XY) and phenotypic normally virilised male. PMDS is transmitted in an autosomal recessive manner, caused by mutations in the anti-Mullerian hormone gene or in the gene encoding the AMH receptor. The authors report a case of a male patient aged 62 years, with bipolar disorder, referred to the endocrinologist by inciden...

Introduction: The usefulness of acute octreotide suppression test (OST) in the selection of patients with acromegaly for chronic somatostatin analogues (SA) treatment is still controversial.Aim: To investigate the predictive value of OST for long-term responsiveness to long-acting SA.Materials and methods: Retrospective study of 25 drug-naive patients (13 males) with active acromegaly, subjected to an OST (hourly serum GH concentra...

Introduction: The aim of this report is to present the uncommon clinical presentation of a patient with a pancreatic NET.Case report: A 55-year-old man with personal history of hypertension, dyslipidaemia, and depression. He was referred to the outpatient for high levels of calcium in repeated assessments during the last year. He referred polyuria and polydipsia. Not clinical history of bone fractures, abdominal pain, or another digestive symptoms. Initi...

Objective: To determine the degree of control of hypercholesterolemia in a specific lipid unit.Material and Methods: Retrospective study of patients followed in our unit over the past 16 years diagnosed with heterozygous familial hypercholesterolemia (HFH) or familial combined hyperlipidemia (FCH). Control criteria according to the following recommendations were compared: International Panel (2003), Nice (2008), NLA (2011), ESC / ESA 2011, Consensus ADA ...

Differentiated thyroid carcinoma is the most common endocrine malignant tumor. Papillary carcinoma frequency in our country is 80% of thyroid neoplasia. Papillary thyroid carcinoma usually metastasizes to cervical lymph. Metastases to distant organs are rare and most often affect the lungs, liver and bones. Despite of its anatomical proximity, metastasis parotid have not been described in the existing papillary carcinomas literature. We report a case of parotid gland metastasi...

Objective: Transition from pediatric to adult health care is a particularly vulnerable period for patients with inborn metabolic diseases.Our objective in this study was to evaluate the current transition of patients with phenylketonuria (PKU) in Malaga, Spain, by analysis of the metabolic control, medical care, patients satisfaction and phychosocial status.Material and methods: We evaluate all the patients transferred to our adult...

Introduction: LH and hCG act on the same receptor (LHCGR), have different half-lives and in vivo biopotency. It is not known whether they elicit the same cellular and molecular response. The aim of this study was to compare the kinetics of cAMP response to recombinant LH and hCG.Design: In COS-7 cells permanently expressing the human LHCGR (COS-7/LHCGR) we evaluated LH and hCG dose-response curves, by measuring total cAMP after 3 h of incubation. ...

Introduction: Metachronic metastasis of renal carcinoma to the thyroid gland, a rare entity occurring sometimes many years after nephrectomy, have been already reported by literature. Thyroidal synchronous metastasis, instead, are more uncommon. We herein report a patient with thyroidal metastasis and intrajugular thrombo embolic involvement as initial presentation of a misunderstood renal carcinoma.Case Report: A 83-years-old woman, with silent medical ...

We present a 27 year-old female patient suffering from multiple sclerosis (MS) since 3 years ago. She currently consults for menstrual disturbances. She has not any neurological secuelae of MS now and she is not on medical treatment. She is with amenorrhea since 10 months ago, but she had been oligomenorrhea just before for 24 months. She doesn’t have any symptoms suspicious for other hormonal impairment. Physical examination is normal.The laborator...